uWSGI seemingly can do a bit of everything, but covering that is a job for the uWSGI documentation. This page covers some basic configuration tasks that may be required just to get your application running, and other tricks you should consider.
If your Python application needs to start within a particular
              directory, use the uWSGI --chdir /starting/path command-line
              option or chdir = /starting/path in your .ini
              file.
If your Python application needs to run within a virtualenv,
              and you didn't already activate that virtualenv to run uWSGI
              itself, point to the virtualenv with the uWSGI -H
              command-line option or with virtualenv = /path/to/virtualenv
              in your .ini file.
uWSGI command-line invocation: --env varname=value
.ini file: env varname=value
If the application hangs while processing a request, you can configure
              uWSGI to destroy the application process handling the request after a timeout
              using the -t seconds command-line option or
              harakiri = seconds in your .ini file.
Some uWSGI configuration examples show this timeout specified without any advice. Consider the following before setting it:
I don't think that processing is helpful for many applications. Refer to the uWSGI FAQ entry on Harakiri mode for more information.
uWSGI can provide statistics in JSON format over a socket, and provides a tool called uwsgitop to maintain a display of activity.
Add stats = 127.0.0.1:port-number to your
              .ini file, then access the stats as follows using netcat
              or uwsgitop:
$ nc 127.0.0.1 9191
{
        "version":"2.0.5",
        "listen_queue":0,
        "listen_queue_errors":0,
        "signal_queue":0,
        "load":0,
        "pid":14600,
        "uid":1,
        "gid":1,
        "cwd":"/home/trawick/myhg/projects/pyweb/app/wsgi",
        "locks":[
...
$ uwsgitop 127.0.0.1:9191
uwsgi-2.0.5 - Sun May 18 16:00:49 2014 - req: 778571 - RPS: 5291 - lq: 0 - tx: 51.0G
node: trawick-ip - cwd: /home/trawick/myhg/projects/pyweb/app/wsgi - uid: 1 - gid: 1 - masterpid: 14760
 WID    %       PID     REQ     RPS     EXC     SIG     STATUS  AVG     RSS     VSZ     TX      RunT    
 1      14.0    14766   108708  753     0       0       idle    0ms     0       0       7.0G    22275
 2      16.0    14767   124356  868     0       0       idle    0ms     0       0       8.0G    25575
 4      30.4    14769   236788  1596    0       0       busy    0ms     0       0       15.0G   49106
 3      39.7    14768   308719  2074    0       0       busy    0ms     0       0       20.0G   64232